PHOSPHOMUTASES Meaning and
Definition
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Phosphomutases are a group of enzymes that catalyze the transfer of a phosphate group from one position to another within a molecule. They are an essential component of cellular metabolism, regulating the interconversion of phosphorylated compounds. The process of phosphorylation, which involves the addition of a phosphate group to a molecule, plays a crucial role in many biological processes such as energy production, signal transduction, and enzyme regulation.
Phosphomutases work by transferring the phosphoryl group within a substrate molecule without the involvement of ATP (adenosine triphosphate). These enzymes typically utilize a covalently bound phosphorylated intermediate during the catalytic cycle. They are classified based on the position of the phosphate group they transfer, such as phosphoglycerate mutase, phosphocreatine mutase, and phosphohexose mutase.
The activity of phosphomutases is tightly regulated to maintain the balance of phosphorylated molecules within the cell. Any disruption in their functionality can lead to cellular dysfunction and disease. For example, deficiencies in certain phosphomutases have been associated with metabolic disorders such as glycogen storage diseases.
Overall, phosphomutases play a crucial role in the regulation of cellular metabolism by transferring phosphate groups between different positions within a molecule. Their activity is essential for maintaining normal cellular function and disruption in their function can have detrimental effects on cellular processes.
Common Misspellings for PHOSPHOMUTASES
- ohosphomutases
- lhosphomutases
- -hosphomutases
- 0hosphomutases
- pgosphomutases
- pbosphomutases
- pnosphomutases
- pjosphomutases
- puosphomutases
- pyosphomutases
- phisphomutases
- phksphomutases
- phlsphomutases
- phpsphomutases
- ph0sphomutases
- ph9sphomutases
- phoaphomutases
- phozphomutases
- phoxphomutases
- phodphomutases
Etymology of PHOSPHOMUTASES
The term "phosphomutases" is derived from the combination of two parts: "phospho" and "mutases".
1. "Phospho" comes from the Greek word "phosphoros" (φωσφόρος), meaning "light-bringer" or "light-bearing". This term is often associated with the element phosphorus due to its characteristic property of glowing in the dark when exposed to air. In biological terms, "phospho" refers to the addition or removal of phosphate groups in molecules, such as proteins or enzymes, which play essential roles in cellular signaling and energy metabolism.
2. "Mutases" originates from the term "mutate" or "mutation", which comes from the Latin word "mutare", meaning "to change" or "to exchange".
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