PHOSPHATASE CALCINEURIN Meaning and
Definition
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Phosphatase calcineurin, also known as calcineurin, is an enzyme that belongs to the class of serine/threonine phosphatases. It is a calcium/calmodulin-dependent protein phosphatase, meaning its activity is regulated by the presence of calcium ions and the calcium-binding protein calmodulin. Calcineurin is primarily found in the cytoplasm of cells but can also be present in other cellular compartments.
The main function of phosphatase calcineurin is to regulate various signaling pathways in cells. It is involved in dephosphorylating and therefore activating or inactivating various downstream signaling molecules. One of the most prominent roles of calcineurin is its regulation of the nuclear factor of activated T-cells (NFAT) family of transcription factors. By dephosphorylating NFAT, calcineurin enables its translocation into the nucleus, allowing it to regulate the expression of specific genes involved in cellular processes such as immune response and development.
Phosphatase calcineurin has been widely studied and implicated in a range of biological processes, including T-cell activation, neuronal development, muscle function, and cardiac hypertrophy. Dysfunction of calcineurin activity has been associated with a number of diseases, such as neurodegenerative disorders, autoimmune diseases, and cardiac diseases.
Overall, phosphatase calcineurin is an essential enzyme for cellular signaling modulation, and its regulatory function plays a critical role in a wide array of physiological processes throughout the body.
Common Misspellings for PHOSPHATASE CALCINEURIN
- ohosphatase calcineurin
- lhosphatase calcineurin
- 0hosphatase calcineurin
- pgosphatase calcineurin
- pbosphatase calcineurin
- pnosphatase calcineurin
- pjosphatase calcineurin
- puosphatase calcineurin
- pyosphatase calcineurin
- phisphatase calcineurin
- phksphatase calcineurin
- phlsphatase calcineurin
- phpsphatase calcineurin
- ph0sphatase calcineurin
- ph9sphatase calcineurin
- phoaphatase calcineurin
- phozphatase calcineurin
- phoxphatase calcineurin
- phodphatase calcineurin
- phoephatase calcineurin
Etymology of PHOSPHATASE CALCINEURIN
The word "phosphatase calcineurin" consists of two distinct terms: "phosphatase" and "calcineurin".
1. Phosphatase: The term "phosphatase" derives from the Greek words "phosphoros", meaning "light-bringer" or "illuminate", and "-ase", indicating an enzyme. Phosphatases are enzymes that catalyze the removal of phosphate groups from molecules through hydrolysis.
2. Calcineurin: Calcineurin is a complex term derived from two Latin words. "Calcinare" means "to burn lime" or "to calcinate", while "-in" is a suffix indicating a substance. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase discovered for its role in the immune system and brain development.
