PHLORIZIN HYDROLASE Meaning and
Definition
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Phlorizin hydrolase is an enzyme, also known as an enzyme-catalyzed carboxylic ester hydrolase, belonging to the family of hydrolases. It is primarily found within the brush border membrane of the small intestine, specifically in the microvilli of the enterocytes. This enzyme participates in the metabolism of phlorizin, a naturally occurring glucoside compound found in plants such as apple or pear trees.
Phlorizin hydrolase plays a crucial role in the dietary regulation of glucose absorption in the small intestine. It functions by catalyzing the cleavage of phlorizin into two main components: glucose and phloretin. Glucose can then be easily absorbed by the enterocytes through the glucose transporters present in the intestinal lining. Phloretin, on the other hand, is not absorbed and is subsequently excreted.
The activity of phlorizin hydrolase is particularly important in the management of diabetes. By cleaving phlorizin into glucose and phloretin, this enzyme limits the absorption of glucose into the bloodstream. This mechanism helps in controlling blood sugar levels and preventing hyperglycemia. Additionally, by promoting the excretion of phloretin, this enzyme further prevents its potential harmful effects.
Overall, phlorizin hydrolase is essential for the efficient absorption and regulation of glucose in the small intestine. Its activity is paramount in the management of diabetes and understanding its mechanisms can provide insights into the development of therapeutic strategies to control blood sugar levels.
Common Misspellings for PHLORIZIN HYDROLASE
- ohlorizin hydrolase
- lhlorizin hydrolase
- -hlorizin hydrolase
- 0hlorizin hydrolase
- pglorizin hydrolase
- pblorizin hydrolase
- pnlorizin hydrolase
- pjlorizin hydrolase
- pulorizin hydrolase
- pylorizin hydrolase
- phkorizin hydrolase
- phporizin hydrolase
- phoorizin hydrolase
- phlirizin hydrolase
- phlkrizin hydrolase
- phllrizin hydrolase
- phlprizin hydrolase
- phl0rizin hydrolase
- phl9rizin hydrolase
- phloeizin hydrolase
Etymology of PHLORIZIN HYDROLASE
The word "Phlorizin Hydrolase" is derived from two parts: "Phlorizin" and "Hydrolase".
- "Phlorizin" refers to a compound known as phloridzin, which is a natural plant substance found in the bark and fruits of apple and pear trees. It belongs to the class of compounds known as dihydrochalcones and has been used in medical research for its potential health benefits.
- "Hydrolase" is a suffix in biochemistry that indicates the enzyme's function to catalyze the hydrolysis of a specific chemical bond within a molecule. In this case, "hydrolase" indicates that the enzyme has the ability to break down or cleave phlorizin into its constituent parts.
