How Do You Spell PHENYLALANINE HYDROXYLASE?

Pronunciation: [fˌiːna͡ɪlˈalɐnˌa͡ɪn hˈa͡ɪdɹəksˌɪle͡ɪs] (IPA)

The word "Phenylalanine Hydroxylase" is a mouthful to pronounce and spell. It is a key enzyme responsible for breaking down phenylalanine in the body. The spelling of this word can be explained using the IPA phonetic transcription - /fəˌnɪləˈleɪnɪn haɪˈdrɑksəleɪz/. The first syllable starts with a short "u" sound, followed by the "n" sound. The next syllable starts with the "i" sound, with a short "e" sound following it. The third syllable starts with the "l" sound, followed by the long "a" sound. The next two syllables are pronounced similarly, starting with the "h" sound, followed by the long "i" sound. The final syllable starts with the "z" sound,

PHENYLALANINE HYDROXYLASE Meaning and Definition

1. Phenylalanine Hydroxylase (PAH) is an enzyme found in the body that plays a crucial role in the metabolism of the essential amino acid phenylalanine. It is primarily found in the liver, where it converts phenylalanine to another amino acid called tyrosine.

   Phenylalanine is obtained through the diet and is necessary for the synthesis of various proteins in the body. However, individuals with a deficiency in PAH are unable to properly convert phenylalanine, resulting in a condition known as phenylketonuria (PKU).

   PKU is an inherited disorder characterized by the accumulation of excess phenylalanine in the blood and body tissues. This buildup of phenylalanine can lead to a variety of symptoms and health complications, including intellectual disabilities, developmental delays, seizures, and behavioral problems.

   The function of phenylalanine hydroxylase is crucial in managing PKU. It catalyzes the hydroxylation of phenylalanine to form tyrosine, which can then be further metabolized into neurotransmitters, hormones, and other important molecules in the body. Treatment for PKU often involves a strict low-phenylalanine diet and the use of synthetic formulas or medical foods to provide the necessary nutrients while restricting phenylalanine intake.

   In summary, phenylalanine hydroxylase is an important enzyme responsible for metabolizing phenylalanine into tyrosine. Deficiency or dysfunction of this enzyme can result in phenylketonuria, a genetic disorder that requires dietary management to prevent the buildup of phenylalanine in the body.

Common Misspellings for PHENYLALANINE HYDROXYLASE

• ohenylalanine hydroxylase
• lhenylalanine hydroxylase
• -henylalanine hydroxylase
• 0henylalanine hydroxylase
• pgenylalanine hydroxylase
• pbenylalanine hydroxylase
• pnenylalanine hydroxylase
• pjenylalanine hydroxylase
• puenylalanine hydroxylase
• pyenylalanine hydroxylase
• phwnylalanine hydroxylase
• phsnylalanine hydroxylase
• phdnylalanine hydroxylase
• phrnylalanine hydroxylase
• ph4nylalanine hydroxylase
• ph3nylalanine hydroxylase
• phebylalanine hydroxylase
• phemylalanine hydroxylase
• phejylalanine hydroxylase
• phehylalanine hydroxylase

Etymology of PHENYLALANINE HYDROXYLASE

The word "Phenylalanine Hydroxylase" is derived from two main components - "phenylalanine" and "hydroxylase".

1. Phenylalanine: This term originates from the combination of two words - "phenyl" and "alanine".

- "Phenyl" comes from the Greek word "phaino", meaning "to appear" or "to shine". It is often used in chemistry to refer to an aromatic compound with a benzene ring.

- "Alanine" is an amino acid, named after the Latin word "alumen", meaning "alum".

2. Hydroxylase: This word is derived from the combination of "hydroxyl" and the suffix "-ase", which denotes an enzyme.