Phage IKe is a specific bacteriophage, a virus that infects and replicates within bacteria. It belongs to the family Myoviridae and the genus T4-like viruses, which are characterized by large, contractile tails and icosahedral heads. Phage IKe is specifically classified as a T4 supergroup phage due to its genetic similarities to the well-studied bacteriophage T4.
This phage was first isolated from environmental samples and subsequently studied extensively due to its importance in bacteriophage research. Phage IKe is known for its broad host range, meaning it can infect and lyse various bacterial species. It targets Escherichia coli strains, including those used in scientific research and industrial processes.
In terms of structure, Phage IKe possesses a complex, multi-layered head, encapsulating its genetic material consisting of double-stranded DNA. Its long tail is comprised of a contractile sheath that enables efficient attachment to bacteria during the infection process. Phage IKe's replication cycle follows the classical bacteriophage infection pathway, including adsorption, penetration, synthesis of viral components, assembly, and release by host lysis.
Due to its broad host range, Phage IKe has been instrumental in numerous scientific studies investigating bacteriophage biology, genetics, and evolution. Moreover, it has significant potential for the development of bacteriophage-based therapies to combat bacterial infections, as it demonstrates efficient lytic capabilities against various strains of bacteria, including common pathogens.
