The spelling of "pertusses" can be confusing for many people. It is derived from the Latin word "pertussis" which means a whooping cough. The pronunciation of this word is /pɜːtʊsɪz/, where the "er" sound is pronounced as the "ur" in "turn" and the first "s" is pronounced as "z". In some regions, this word is spelled as "pertussis". Regardless of the spelling, it refers to a highly contagious respiratory disease that can be prevented by vaccination.