PEROXYNITRITES Meaning and
Definition
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Peroxynitrites are a class of highly reactive nitrogen-containing molecules that consist of a peroxide group (O-O) connected to the nitrite group (NO2). They are formed through the reaction between nitric oxide (NO) and superoxide anion (O2-), two free radicals found in the body. Peroxynitrites are known to possess potent biological activities, acting as signaling molecules and regulators of various cell functions.
In biological systems, peroxynitrites have been found to be involved in numerous physiological and pathological processes. They play a crucial role in modulating the signaling pathways of immune cells, such as macrophages and neutrophils, contributing to the body's defense against infections and inflammation. However, under certain conditions, the excessive production of peroxynitrites can lead to oxidative damage and tissue injury.
Peroxynitrites are highly reactive species that readily react with a wide range of biomolecules, including lipids, proteins, and DNA, leading to oxidative modifications and possible disruption of cellular function. This oxidative stress caused by peroxynitrites has been implicated in the development and progression of various diseases, including cardiovascular disorders, neurodegenerative diseases, and cancer.
To study the levels and effects of peroxynitrites in biological systems, researchers employ different analytical techniques, such as fluorescent probes and mass spectrometry, to detect and quantify these reactive molecules. Additionally, various antioxidants and scavengers have been developed to counteract the detrimental effects of peroxynitrites in order to protect cellular integrity and prevent associated pathological conditions.
Common Misspellings for PEROXYNITRITES
- oeroxynitrites
- leroxynitrites
- -eroxynitrites
- 0eroxynitrites
- pwroxynitrites
- psroxynitrites
- pdroxynitrites
- prroxynitrites
- p4roxynitrites
- p3roxynitrites
- peeoxynitrites
- pedoxynitrites
- pefoxynitrites
- petoxynitrites
- pe5oxynitrites
- pe4oxynitrites
- perixynitrites
- perkxynitrites
- perlxynitrites
- perpxynitrites
Etymology of PEROXYNITRITES
The word "peroxynitrites" is derived from the combination of two separate terms: "peroxynitrite" and the suffix "-s".
1. Peroxynitrite: The term "peroxynitrite" is formed by combining two words – "peroxy" and "nitrite".
- Peroxy: Derived from the Greek word "peroxus", meaning "very sharp" or "acid", it is used to indicate the presence of the peroxide group (-O-O-).
- Nitrite: Referring to a compound consisting of nitrogen and oxygen, the term "nitrite" originates from the Latin word "nitrum" meaning "sodium carbonate" or "saltpeter".
2. The suffix "-s": The addition of the suffix "-s" in the word "peroxynitrites" denotes pluralization, indicating multiple peroxynitrite molecules or compounds.
