How Do You Spell PEPTIDYLTRANSFERASE?

Pronunciation: [pˈɛptɪdˌɪltɹɐnsfˌɜːɹe͡ɪz] (IPA)

Peptidyltransferase is a key enzyme involved in protein synthesis. The word is spelled as /ˌpɛptɪˈdaɪlˌtrænsfəreɪs/ using the International Phonetic Alphabet. The initial "p" is pronounced as /p/ and the following "e" is pronounced as /ɛ/. The "pt" cluster is pronounced together as /pt/. The "i" is pronounced as /ɪ/, followed by "d" pronounced as /d/. The "a" sound is pronounced as /ə/. Finally, "transferase" is spelled with the same pronunciation as /ˈtrænsfəreɪs/.

PEPTIDYLTRANSFERASE Meaning and Definition

1. Peptidyltransferase is an enzymatic activity found in ribosomes that catalyzes the transfer of peptidyl groups from one amino acid to another during protein synthesis. Specifically, it is responsible for the formation of peptide bonds between the amino acid residues within the growing polypeptide chain.

   The peptidyltransferase activity occurs in the large subunit of the ribosome, composed of RNA molecules (rRNA) and protein subunits. It is primarily facilitated by a specific rRNA component known as the 23S rRNA. The precise mechanism of peptidyltransferase involves the positioning of the aminoacyl-tRNA (tRNA carrying the new amino acid to be added) and the peptidyl-tRNA (tRNA carrying the nascent polypeptide chain) in close proximity, allowing the transfer of the peptidyl group to occur.

   This enzymatic activity plays a crucial role in the elongation stage of protein synthesis, ensuring accurate and sequential incorporation of amino acids into the growing polypeptide chain based on the codons of mRNA. The peptidyltransferase activity is essential for the overall structure and function of proteins, as it determines the order and arrangement of the amino acids, leading to the formation of specific three-dimensional structures and protein folding.

   Overall, peptidyltransferase is a fundamental enzymatic activity that is vital for protein synthesis and the production of functional proteins in living organisms.

Common Misspellings for PEPTIDYLTRANSFERASE

• oeptidyltransferase
• leptidyltransferase
• -eptidyltransferase
• 0eptidyltransferase
• pwptidyltransferase
• psptidyltransferase
• pdptidyltransferase
• prptidyltransferase
• p4ptidyltransferase
• p3ptidyltransferase
• peotidyltransferase
• peltidyltransferase
• pe-tidyltransferase
• pe0tidyltransferase
• pepridyltransferase
• pepfidyltransferase
• pepgidyltransferase
• pepyidyltransferase
• pep6idyltransferase
• pep5idyltransferase

Etymology of PEPTIDYLTRANSFERASE

The word "Peptidyltransferase" is derived from a combination of two components: "peptidyl" and "transferase".

1. Peptidyl: This part of the word comes from "peptide", which refers to a chain of amino acids connected by peptide bonds. It is derived from the Greek word "peptos", meaning "digested" or "cooked". In modern usage, "peptide" is a term used to describe short chains of amino acids, typically containing less than 50 amino acids.

2. Transferase: This part of the word comes from the Latin word "transferre", meaning "to carry across" or "to transfer". In biochemistry, a transferase is an enzyme that facilitates the transfer of a functional group, such as a phosphate or methyl group, from one molecule to another.