PENTOSE SHUNT Meaning and
Definition
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The pentose phosphate pathway, also known as the pentose shunt, is a metabolic pathway that occurs in the cytoplasm of cells and is involved in the metabolism of glucose. It is an alternative pathway to glycolysis and plays a crucial role in generating reducing power in the form of NADPH for biosynthetic processes and in producing ribose-5-phosphate (a precursor for nucleotide synthesis) in cells.
The pentose shunt consists of two phases: the oxidative phase and the non-oxidative phase. In the oxidative phase, glucose-6-phosphate is converted to ribulose-5-phosphate through a series of enzymatic reactions that generate two molecules of NADPH. This phase also produces other intermediates such as ribose-5-phosphate and sedoheptulose-7-phosphate that can be used in various biosynthetic pathways.
The non-oxidative phase of the pentose shunt involves a rearrangement of the sugar phosphates produced in the oxidative phase. By utilizing a set of enzymes, the non-oxidative phase allows for the interconversion of different sugar phosphate molecules, which can be used for energy production or as building blocks in various biochemical reactions.
Overall, the pentose shunt provides a means for cells to generate NADPH and synthesize nucleotides while simultaneously fulfilling the energy needs of the cell. This pathway is particularly important in tissues with high rates of nucleotide synthesis, such as the liver, bone marrow, and rapidly dividing cells.
Common Misspellings for PENTOSE SHUNT
- oentose shunt
- lentose shunt
- -entose shunt
- 0entose shunt
- pwntose shunt
- psntose shunt
- pdntose shunt
- prntose shunt
- p4ntose shunt
- p3ntose shunt
- pebtose shunt
- pemtose shunt
- pejtose shunt
- pehtose shunt
- penrose shunt
- penfose shunt
- pengose shunt
- penyose shunt
- pen6ose shunt
- pen5ose shunt
Etymology of PENTOSE SHUNT
The term "Pentose Shunt" is derived from the combination of two elements:
1. Pentose: The word "pentose" refers to a type of sugar molecule that contains five carbon atoms. The term is derived from the Greek word "pent" meaning "five" and the suffix "-ose" indicating a sugar. Pentoses are important components of nucleic acids and various coenzymes in living organisms.
2. Shunt: In this context, the term "shunt" refers to a metabolic pathway in which certain compounds are diverted or rerouted from their usual course. The word "shunt" comes from the Middle English word "shunten" meaning "to move suddenly", which originated from the Old English and Old Norse words with similar meanings.
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