PATHOLOGICAL NEOVASCULARIZATION Meaning and
Definition
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Pathological neovascularization refers to the excessive formation of new blood vessels in abnormal locations or quantities, typically associated with certain diseases or conditions. Neovascularization generally occurs as a normal physiological response to tissue injury or low oxygen levels, aiming to increase blood supply and facilitate wound healing. However, in the case of pathological neovascularization, this process becomes dysregulated and excessive, resulting in the growth of abnormal blood vessels that are fragile and prone to leaking.
Pathological neovascularization commonly occurs in several medical conditions, such as age-related macular degeneration (AMD), diabetic retinopathy, and certain types of cancer, particularly solid tumors. In these diseases, the new blood vessels formed are often weak and irregularly arranged, compromising the structural integrity of tissues and impairing their normal functions. This can lead to severe complications, including bleeding, edema, and tissue damage.
Understanding the mechanisms behind pathological neovascularization is crucial for developing effective treatment strategies. Various signaling pathways and growth factors have been implicated in this process, including vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF). Therapeutic interventions targeting these pathways, such as anti-VEGF medications, have been developed to suppress the abnormal blood vessel growth and mitigate the associated complications.
Overall, pathological neovascularization refers to the abnormal formation of blood vessels in response to certain diseases or conditions. It is characterized by the growth of fragile and disorganized blood vessels, leading to tissue damage and functional impairment.
Common Misspellings for PATHOLOGICAL NEOVASCULARIZATION
- oathological neovascularization
- lathological neovascularization
- -athological neovascularization
- 0athological neovascularization
- pzthological neovascularization
- psthological neovascularization
- pwthological neovascularization
- pqthological neovascularization
- parhological neovascularization
- pafhological neovascularization
- paghological neovascularization
- payhological neovascularization
- pa6hological neovascularization
- pa5hological neovascularization
- patgological neovascularization
- patbological neovascularization
- patnological neovascularization
- patjological neovascularization
- patuological neovascularization
- patyological neovascularization
Etymology of PATHOLOGICAL NEOVASCULARIZATION
The etymology of the word "pathological neovascularization" can be broken down as follows:
1. Pathological: The term "pathological" originates from the Greek word "pathos", which means "suffering" or "disease". It is combined with the suffix "-logical", which refers to the study or science of a particular subject. Thus, "pathological" refers to the study or science of diseases.
2. Neo: The term "neo" comes from the Greek word "neos", which means "new" or "recent". It is commonly used as a prefix to indicate something new, modern, or innovative.
3. Vascularization: The word "vascularization" is derived from the Latin word "vasculum", which means "blood vessel". It is combined with the suffix "-ization", which denotes the process or act of something.
