The word Pasteurella tularensis is spelled using the International Phonetic Alphabet (IPA) to ensure uniformity in the pronunciation of the word. The first syllable, "pas-", is pronounced as "pæs" (with a short "a" sound), followed by "tu-" pronounced as "tjʊ" (with a "j" sound). The second syllable, "re-", is pronounced as "riː" (with a long "e" sound), followed by "lla" pronounced as "lə". Finally, the last syllable "sis" is pronounced as "sɪs". Overall, the word is pronounced as "pæstjʊˈriːlə tʃʊləˈrɛnsɪs".
Pasteurella tularensis is a gram-negative bacterium that belongs to the Pasteurellaceae family and is the causative agent of tularemia. This highly virulent bacterium is named after the French microbiologist Louis Pasteur and the region where it was first identified, Tulare County in California. P. tularensis is zoonotic in nature, meaning it primarily infects animals but can also be transmitted to humans through various routes.
The bacterium possesses a small, nonmotile, rod-shaped structure and is capable of surviving both inside and outside animal hosts. It can be found in a wide range of animals, such as rabbits, hares, rodents, and birds, where it can cause severe disease. In humans, P. tularensis infection can occur through direct contact with an infected animal or its carcass, inhalation of contaminated dust or aerosols, ingestion of contaminated food or water, or through tick or mosquito bites.
Once P. tularensis enters the human body, it can cause a variety of clinical manifestations depending on the route of entry and the individual's immune response. Tularemia can present itself as a localized infection, such as ulceroglandular tularemia, or as a systemic infection affecting multiple organ systems, known as typhoidal tularemia. The symptoms can include fever, chills, headache, muscle aches, swollen lymph nodes, and in severe cases, respiratory distress and organ failure.
Due to its high infectivity, P. tularensis is considered a potential bioweapon, making its study and surveillance critically important in terms of public health preparedness.
The word "Pasteurella tularensis" has its etymology rooted in the names of two scientists and the disease they studied.
The genus name "Pasteurella" is derived from the last name of Louis Pasteur, a prominent French scientist known for his groundbreaking work in microbiology and immunization. In the late 19th century, Pasteur made significant contributions to the field of bacteriology, specifically in the study of diseases caused by bacteria.
The species name "tularensis" is derived from "Tularemia", which is the disease caused by the bacterium Pasteurella tularensis. Tularemia is a rare infectious disease that affects many mammals, including humans. The name "tularensis" is derived from the location where the disease was first identified in the United States – Tulare County, California.