PARTIAL MONOSOMY Meaning and
Definition
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Partial monosomy is a chromosomal abnormality characterized by the loss of a part of one chromosome pair, resulting in an individual having only one copy of that segment instead of the usual two copies. This condition is also referred to as a deletion or terminal deletion.
The loss of genetic material that occurs in partial monosomy can vary in size and location, depending on the specific chromosome involved. It typically leads to various physical and developmental abnormalities in affected individuals. The severity of these abnormalities can vary widely depending on the specific genes that are deleted.
Partial monosomy can be inherited from a parent who carries a structural rearrangement of chromosomes, such as a balanced translocation or an inversion. It can also arise as a result of spontaneous chromosomal breakage and loss during fetal development. In some cases, the loss of genetic material may be restricted to a specific group of cells in the body, known as mosaicism.
Some common clinical manifestations of partial monosomy include growth retardation, intellectual disabilities, distinct facial features, heart defects, and other organ abnormalities. The diagnosis of partial monosomy is typically confirmed through chromosomal analysis, such as karyotyping or array comparative genomic hybridization (CGH). Treatment for individuals with partial monosomy mainly focuses on managing the associated symptoms and may involve the expertise of multiple medical specialists, including geneticists, pediatricians, cardiologists, and psychologists.
Overall, partial monosomy is a genetic condition characterized by the loss of genetic material from a specific chromosome resulting in various physical and developmental abnormalities.
Common Misspellings for PARTIAL MONOSOMY
- oartial monosomy
- lartial monosomy
- -artial monosomy
- 0artial monosomy
- pzrtial monosomy
- psrtial monosomy
- pwrtial monosomy
- pqrtial monosomy
- paetial monosomy
- padtial monosomy
- paftial monosomy
- pattial monosomy
- pa5tial monosomy
- pa4tial monosomy
- parrial monosomy
- parfial monosomy
- pargial monosomy
- paryial monosomy
- par6ial monosomy
- par5ial monosomy
Etymology of PARTIAL MONOSOMY
The word "partial" comes from the Latin word "partialis", which means "related to a part". It is derived from the Latin word "pars", meaning "part".
The term "monosomy" is derived from the Greek words "mono", meaning "single", and "soma", meaning "body" or "chromosome".
So, "Partial Monosomy" refers to a condition in which there is a loss or deletion of a portion of one chromosome, resulting in the presence of only a single copy of that specific chromosome segment instead of the usual pair.
