Paraganglioma is a rare type of tumor that can occur in different parts of the body, including the head, neck, abdomen and pelvis. The word paraganglioma is spelled using the International Phonetic Alphabet (IPA) phonetic transcription [ˌpærəˌɡæŋɡliˈoʊmə]. The stressed syllables are "pa-ra-gan-GLI-o-ma," with a soft "g" sound in the middle. This spelling follows the rules of English phonetics, where each letter is pronounced individually and each syllable has equal stress. Accurate spelling of medical terms like paraganglioma is important to ensure clear and effective communication between healthcare professionals.
A paraganglioma is a benign or malignant tumor that originates from the paraganglia, which are small clusters of specialized cells located near certain blood vessels and nerves in various locations of the body. These tumors can develop in several places, including the head, neck, chest, abdomen, and pelvis.
Paragangliomas are typically slow-growing and noncancerous (benign), but in some cases, they may become cancerous (malignant). They often go undetected until they grow large enough to produce noticeable symptoms. Common symptoms may include high blood pressure, palpitations, headaches, sweating, flushing, anxiety, weight loss, and abdominal pain.
The exact cause of paragangliomas is currently unknown, but they are thought to be associated with genetic mutations that can be inherited or acquired. In some cases, paragangliomas are associated with hereditary syndromes such as multiple endocrine neoplasia type 2 and von Hippel-Lindau syndrome.
Diagnosis of paragangliomas typically involves imaging tests such as CT scans, MRI scans, and/or nuclear medicine scans. Biopsy is often required to confirm the diagnosis and determine whether the tumor is benign or malignant.
Treatment for paragangliomas depends on various factors such as tumor location, size, presence of symptoms, and whether the tumor is benign or malignant. Options may include surgery, radiation therapy, embolization, chemotherapy, or targeted therapy, depending on the specific situation. Regular follow-up and monitoring are crucial because paragangliomas can recur even after treatment.
A new growth arising from the medullary portion of an adrenal gland.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "paraganglioma" is derived from two components: "para-" and "ganglioma".
The prefix "para-" comes from the Greek word "παρά" (para), which means "beside" or "near". In medical terminology, the prefix "para-" is often used to indicate something that is next to or associated with something else.
The term "ganglioma" is formed by combining the Greek word "γάγγλιος" (ganglios), which means "swelling" or "knot", with the suffix "-oma", which is commonly used in medicine to denote a swelling, tumor, or abnormal growth.
Therefore, the word "paraganglioma" refers to a type of tumor or swelling that develops near or next to a ganglion, which is a cluster of nerve cells.