How Do You Spell PAH TRANSPORTER?

Pronunciation: [pˌiːˌe͡ɪˈe͡ɪt͡ʃ tɹanspˈɔːtə] (IPA)

The word "PAH transporter" is pronounced /piː eɪ ˈeɪtʃ trænsˈpɔːtə/. The first two letters, "PA," are pronounced as a single syllable, with the "P" sound followed by the "A" sound. The "H" is pronounced separately, and the rest of the word is pronounced as "transporter." The phonetic transcription helps to clarify the pronunciation of this word, which is important for understanding its meaning in scientific contexts where it is commonly used.

PAH TRANSPORTER Meaning and Definition

1. PAH Transporter:

   A PAH transporter, also known as a p-aminohippurate transporter or an organic anion transporter, is a membrane-bound protein responsible for the transportation of p-aminohippuric acid (PAH) across cell membranes. PAH transporters are primarily found in the kidneys, although they are also present in other organs such as the liver and the placenta.

   PAH transporters belong to a family of carrier proteins called organic anion transporters (OATs) and are classified as OAT1 and OAT3. These transporters are essential for the renal excretion of PAH, a compound used to measure renal plasma flow in clinical settings. PAH is actively secreted into the tubular fluid of the nephrons by the PAH transporters, facilitating its elimination from the body.

   The function of PAH transporters is crucial for the regulation of various physiological processes. It controls the excretion and clearance of endogenous and exogenous organic anions, including toxins and drugs. By mediating the transport of PAH, these membrane proteins play a vital role in maintaining homeostasis and detoxification.

   Abnormalities in PAH transporter activity can lead to many diseases and disorders. Altered expression or mutations in the genes encoding these transporters can cause drug toxicity, impaired renal function, or even kidney disorders such as renal tubular acidosis.

   Overall, PAH transporters are integral components of the renal system, facilitating the active transport of p-aminohippuric acid and other organic anions across cell membranes. Their crucial role in excretion and clearance makes them vital targets for understanding renal physiology and developing therapeutic strategies for kidney-related conditions.

Common Misspellings for PAH TRANSPORTER

• oah transporter
• lah transporter
• -ah transporter
• 0ah transporter
• pzh transporter
• psh transporter
• pwh transporter
• pqh transporter
• pag transporter
• pab transporter
• pan transporter
• paj transporter
• pau transporter
• pay transporter
• pah rransporter
• pah fransporter
• pah gransporter
• pah yransporter
• pah 6ransporter
• pah 5ransporter

Etymology of PAH TRANSPORTER

The term "PAH transporter" does not have a distinct etymology since it is an abbreviation or acronym for "p-aminohippurate transporter". However, we can analyze the components of the term to understand its origin:

- "PAH" stands for "p-aminohippurate", which is a compound used in medical research to assess the renal plasma flow and the glomerular filtration rate. The term "p-aminohippurate" itself originates from the combination of "p-amino", indicating the presence of an amino group, and "hippurate", which refers to the conjugate base of hippuric acid.

- "Transporter" refers to a protein or molecule involved in the transport of specific substances across cell membranes.

As a result, "PAH transporter" is a term that specifically refers to the protein or molecule responsible for the transport of p-aminohippurate across cell membranes.