Pachymenic is a rarely used medical term that refers to the thickening of tissue. Its spelling can be broken down using the International Phonetic Alphabet as /pəˌkɪmɛnɪk/. The first syllable is pronounced with a short "uh" sound, followed by a stressed "ki" and "men" with a short "e" sound. The final syllable is pronounced with an "ick" sound. This tongue-twister of a word may not roll off the tongue easily but is important in understanding certain medical conditions that result in tissue thickening.
Marked by thickening of the skin or other membranes, pachyhymenic, pachydermatous.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.