P HYDROXYPHENYLPYRUVATE OXIDASE Meaning and
Definition
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P Hydroxyphenylpyruvate Oxidase is an enzyme that plays a crucial role in the metabolism of tyrosine, which is an amino acid involved in the synthesis of various important biomolecules in living organisms. It catalyzes the oxidation of p-hydroxyphenylpyruvate (pHPP) to produce homogentisate.
This enzyme belongs to the class of oxidoreductases, specifically those acting on the CH-OH group of donors with oxygen as the acceptor. It utilizes a cofactor called flavin adenine dinucleotide (FAD) to carry out the oxidation reaction. In this process, FAD accepts two hydrogen atoms from pHPP, resulting in the formation of homogentisate and the reduction of FAD to FADH2.
P Hydroxyphenylpyruvate Oxidase is found in various organisms, including bacteria, plants, and animals. In humans, a deficiency in this enzyme leads to the rare metabolic disorder known as hereditary tyrosinemia type III, which is characterized by the accumulation of pHPP and its derivative, homogentisic acid, in the body.
This enzyme is important as it serves as a key step in the degradation pathway of tyrosine, contributing to the removal of toxic intermediates and the production of essential products. Understanding the structure and function of P Hydroxyphenylpyruvate Oxidase is crucial for developing therapeutic strategies to treat tyrosine-related disorders and for studying the metabolism of tyrosine in various biological systems.
Common Misspellings for P HYDROXYPHENYLPYRUVATE OXIDASE
- o hydroxyphenylpyruvate oxidase
- l hydroxyphenylpyruvate oxidase
- - hydroxyphenylpyruvate oxidase
- 0 hydroxyphenylpyruvate oxidase
- p gydroxyphenylpyruvate oxidase
- p bydroxyphenylpyruvate oxidase
- p nydroxyphenylpyruvate oxidase
- p jydroxyphenylpyruvate oxidase
- p uydroxyphenylpyruvate oxidase
- p yydroxyphenylpyruvate oxidase
- p htdroxyphenylpyruvate oxidase
- p hgdroxyphenylpyruvate oxidase
- p hhdroxyphenylpyruvate oxidase
- p hudroxyphenylpyruvate oxidase
- p h7droxyphenylpyruvate oxidase
- p h6droxyphenylpyruvate oxidase
- p hysroxyphenylpyruvate oxidase
- p hyxroxyphenylpyruvate oxidase
- p hycroxyphenylpyruvate oxidase
- p hyfroxyphenylpyruvate oxidase
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