P AMINOHIPPURATE TRANSPORTER Meaning and
Definition
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The p Aminohippurate Transporter, also known as PAH Transporter, refers to a protein carrier or transmembrane transporter that plays a crucial role in facilitating the movement of p-aminohippurate (PAH) molecules across the cell membrane. PAH is a derivative of the amino acid glycine and is commonly used as a diagnostic tool to measure renal plasma flow in clinical settings.
The p Aminohippurate Transporter is primarily found in the proximal tubules of the kidney, which are responsible for the reabsorption and secretion of various substances. This transporter protein is specifically responsible for the uptake of PAH from the bloodstream into the renal tubular epithelial cells against its concentration gradient. By actively transporting PAH into the cells, the p Aminohippurate Transporter plays a vital role in the renal excretion of PAH from the body.
The p Aminohippurate Transporter operates through a process called active transport, which requires energy in the form of adenosine triphosphate (ATP). It utilizes specialized binding sites to recognize and bind to PAH molecules, enabling their translocation across the cell membrane. This transporter is considered highly specific for PAH and does not interact significantly with other organic anions.
The function of the p Aminohippurate Transporter is crucial for maintaining renal homeostasis and proper kidney function. It allows the efficient elimination of PAH, a substance used clinically to assess renal function, from the body. Dysfunction or impairment of this transporter can lead to altered PAH clearance and potentially contribute to renal disorders, including impaired renal blood flow and kidney disease.
Common Misspellings for P AMINOHIPPURATE TRANSPORTER
- o aminohippurate transporter
- l aminohippurate transporter
- - aminohippurate transporter
- 0 aminohippurate transporter
- p zminohippurate transporter
- p sminohippurate transporter
- p wminohippurate transporter
- p qminohippurate transporter
- p aninohippurate transporter
- p akinohippurate transporter
- p ajinohippurate transporter
- p amunohippurate transporter
- p amjnohippurate transporter
- p amknohippurate transporter
- p amonohippurate transporter
- p am9nohippurate transporter
- p am8nohippurate transporter
- p amibohippurate transporter
- p amimohippurate transporter
- p amijohippurate transporter
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