The spelling of the word "Onophrio" can be explained using the International Phonetic Alphabet (IPA). The first letter, "o," is pronounced as /ɑ/ or "ah." The following letters, "n," "o," and "ph," are pronounced as /n oʊ f/ or "noh-foh." The next letter, "r," is pronounced as /ɹ/ or "r." The final letters, "i" and "o," are pronounced as /i oʊ/ or "ee-oh." Therefore, the correct spelling of "Onophrio" can be pronounced as "ah-noh-foh-r-ee-oh."