How Do You Spell OLD WORLD ARENAVIRUSES?
Pronunciation: [ˈə͡ʊld wˈɜːld ˈaɹɪnˌava͡ɪɹəsɪz] (IPA) 
Pronunciation: [ˈə͡ʊld wˈɜːld ˈaɹɪnˌava͡ɪɹəsɪz] (IPA)
Old World Arenaviruses refer to a group of viruses belonging to the Arenaviridae family that primarily circulate in the Old World, which includes regions of Africa, Europe, and Asia. These viruses are characterized by their unique structure, consisting of a single-stranded RNA genome and an envelope derived from the host cell. The name "arena," referring to sand, was given to these viruses due to the amorphous appearance of the particles under electron microscopy.
Old World Arenaviruses are known to cause several significant diseases in humans and other animals. They are typically transmitted through contact with infected rodents, which serve as reservoir hosts for the viruses. Once transmitted to humans, the viruses can cause various clinical manifestations, ranging from mild to severe.
One of the well-known Old World Arenaviruses is Lassa virus, which causes Lassa fever, a severe and often fatal hemorrhagic fever in West Africa. Another prominent member is Lujo virus, which was identified in Africa and causes an often fatal, rapidly progressing hemorrhagic fever.
The diagnosis of Old World Arenavirus infections usually involves the detection of specific antibodies or viral RNA in patient samples. Treatment options are limited, mainly comprising supportive care measures and symptomatic treatment.
Prevention and control of Old World Arenavirus infections center around practicing good hygiene, minimizing contact with rodents, and following proper biosafety protocols in healthcare settings.
