OKM ANTIGEN Meaning and
Definition
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OKM antigen refers to a complex cell surface marker that is extensively expressed in cells of the monocyte-macrophage lineage. It is a monoclonal antibody (OKM stands for the specific hybridoma cell line that produces this antibody) that recognizes and binds to a specific antigen present on the cell surface of cells derived from hematopoietic stem cells. This antigen is commonly found on the surface of monocytes, macrophages, and certain lymphocytes.
The OKM antigen plays a crucial role in immune responses and is involved in various immune-related functions. It is known to participate in the regulation of cell adhesion, migration, and phagocytosis, which are important processes in immune defense mechanisms. Additionally, the OKM antigen has been implicated in the activation of inflammatory responses and the release of inflammatory mediators.
The OKM antigen is widely used as a specific marker for identifying and characterizing cells of the monocyte-macrophage lineage in experimental studies and clinical settings. Its presence on the surface of these cells enables their separation and isolation for further analysis and investigation. Moreover, the OKM antigen has been utilized in research exploring the role of monocytes and macrophages in various disease processes, including inflammation, infection, and cancer.
In summary, the OKM antigen is a cell surface marker expressed on cells of the monocyte-macrophage lineage that plays vital roles in immune responses and immune-related functions.
Common Misspellings for OKM ANTIGEN
- ok antigen
- ikm antigen
- kkm antigen
- lkm antigen
- pkm antigen
- 0km antigen
- 9km antigen
- ojm antigen
- omm antigen
- olm antigen
- oom antigen
- oim antigen
- okn antigen
- okk antigen
- okj antigen
- okm zntigen
- okm sntigen
- okm wntigen
- okm qntigen
- okm abtigen
Etymology of OKM ANTIGEN
The etymology of the term "OKM antigen" can be traced to the origin of each individual component.
1. OK: The term "OK" is derived from the initials of Othmar Karl Walter Overhoff and his collaborator E. Köhler. Both researchers played a crucial role in the development of monoclonal antibodies, which led to the identification and isolation of the OKM antigens.
2. M: The "M" in OKM stands for the antigen's reactivity with macrophages. Macrophages are a type of white blood cell involved in the immune response and are known to express the OKM antigens on their cell surfaces.
Therefore, the term "OKM antigen" emerged as a result of its association with Overhoff, Köhler, and its reactivity with macrophages.
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