How Do You Spell NUCLEOTIDE DEAMINASES?

Pronunciation: [njˈuːklɪˌɒta͡ɪd dˈiːmɪnˌe͡ɪsɪz] (IPA)

Nucleotide deaminases are enzymes that catalyze the removal of an amino group from nucleotides, resulting in their conversion to different molecules. The spelling of this word is based on the International Phonetic Alphabet (IPA), a system of symbols representing speech sounds. "Nucleotide" is pronounced /ˈnjuːklɪətaɪd/ (NOO-klee-uh-tied), "deaminases" is pronounced /diːˈæmɪneɪsɪz/ (dee-AM-in-ay-siz). To correctly pronounce this word, emphasize the first syllable of nucleotide and the second syllable of deaminases. This is a crucial term in the field of genetics and biochemistry, important for understanding DNA and RNA metabolism.

NUCLEOTIDE DEAMINASES Meaning and Definition

1. Nucleotide deaminases are a group of enzymes that catalyze the removal of an amino group (NH2) from nucleotides, resulting in the formation of a new compound with a deaminated nucleotide structure. Deamination is a chemical process in which an amino group is replaced by a carbonyl group, leading to alterations in the chemical composition and properties of the nucleotide.

   These enzymes play a crucial role in various biological processes, including DNA repair, RNA editing, and immune response. Nucleotide deaminases are involved in maintaining the integrity of genetic material by recognizing and eliminating damaged or inappropriate nucleotides from DNA or RNA molecules. By removing the amino group, they generate modified nucleotides that can subsequently be recognized and repaired by specific enzymes or pathways.

   One well-known example of nucleotide deaminases is the activation-induced cytidine deaminase (AID), which is involved in the immune response by initiating somatic hypermutation and class-switch recombination in antibody genes. AID catalyzes the deamination of cytidine to generate uridine, leading to the diversification of antibody molecules.

   Overall, nucleotide deaminases are important enzymes that act on nucleotides, modifying their structures and participating in critical biological processes. Their deamination activity allows for the precise regulation, repair, and diversification of nucleic acids, contributing to the overall functionality and adaptability of living organisms.

Common Misspellings for NUCLEOTIDE DEAMINASES

• nucleodide deaminases
• bucleotide deaminases
• mucleotide deaminases
• jucleotide deaminases
• hucleotide deaminases
• nycleotide deaminases
• nhcleotide deaminases
• njcleotide deaminases
• nicleotide deaminases
• n8cleotide deaminases
• n7cleotide deaminases
• nuxleotide deaminases
• nuvleotide deaminases
• nufleotide deaminases
• nudleotide deaminases
• nuckeotide deaminases
• nucpeotide deaminases
• nucoeotide deaminases
• nuclwotide deaminases
• nuclsotide deaminases

Etymology of NUCLEOTIDE DEAMINASES

The word "nucleotide deaminases" can be broken down into two parts: "nucleotide" and "deaminases".

The word "nucleotide" comes from the Latin word "nucleus", meaning "kernel" or "core", and the Greek word "tides", meaning "a suffix denoting a class or group". In biology, a nucleotide is a compound consisting of a nucleoside (a nitrogenous base attached to a sugar) bonded to a phosphate group. Nucleotides are the building blocks of nucleic acids like DNA and RNA.

The term "deaminases" is derived from the word "deaminate", which comes from the Latin word "deaminare", meaning "to remove an amino group". An amino group is a functional group (-NH2) consisting of a nitrogen atom bonded to two hydrogen atoms.