How Do You Spell NUCLEOSIDASE?

Pronunciation: [njˈuːklɪˌɒsɪdˌe͡ɪs] (IPA)

The word "nucleosidase" is spelled with the IPA phonetic transcription /ˌnjuːkliˈɑːsɪdeɪz/. This enzyme is responsible for catalyzing the hydrolysis of nucleosides into nucleobases and ribose or deoxyribose. The spelling of this word can be broken down into its individual phonemes, which include the voiced alveolar nasal /n/, the close back unrounded vowel /u/, the voiceless velar plosive /k/, the voiced alveolar lateral approximant /l/, the close front unrounded vowel /i/, the open-mid back unrounded vowel /ɑː/, the voiceless alveolar fricative /s/, the close front unrounded vowel /i/, the voiced alveolar fricative /d/, the diphthong ending with /

NUCLEOSIDASE Meaning and Definition

1. Nucleosidase is an enzyme that plays a vital role in the metabolism of nucleosides. A nucleoside is a molecule composed of a purine or pyrimidine base linked to a sugar molecule, usually ribose or deoxyribose. Nucleosides are the building blocks of nucleic acids like DNA and RNA.

   Nucleosidases are responsible for the hydrolysis of nucleosides, resulting in the separation of the base and sugar components. This enzymatic reaction involves the addition of water molecules to the nucleoside, leading to the breakdown of the glycosidic bond that connects the base and sugar moieties. As a result, nucleosidases contribute to the recycling of nucleosides by releasing the base that can be further utilized in various cellular processes.

   These enzymes are mainly found in various tissues and organs, including the liver, kidneys, intestines, and blood cells. They are also present in microorganisms and play a role in nucleotide metabolism. Nucleosidases have different specificity to recognize and hydrolyze specific nucleosides depending on the organism and physiological conditions. For example, adenosine deaminase is a specific nucleosidase that acts on adenosine, converting it into inosine.

   The activity of nucleosidases can be influenced by various factors, including pH, temperature, cofactors, and inhibitors. Dysregulation or deficiency of nucleosidase activity can lead to various disorders, such as nucleoside toxicity or accumulation, affecting normal cellular processes. Therefore, understanding nucleosidase function and regulation is essential for studying nucleotide metabolism, as well as potential therapeutic interventions targeting nucleoside-related diseases.

Common Misspellings for NUCLEOSIDASE

• bucleosidase
• mucleosidase
• jucleosidase
• hucleosidase
• nycleosidase
• nhcleosidase
• njcleosidase
• nicleosidase
• n8cleosidase
• n7cleosidase
• nuxleosidase
• nuvleosidase
• nufleosidase
• nudleosidase
• nuckeosidase
• nucpeosidase
• nucoeosidase
• nuclwosidase
• nuclsosidase
• nucldosidase

Etymology of NUCLEOSIDASE

The word "nucleosidase" is derived from the combination of two components: "nucleo-" and "-sidase".

The term "nucleo-" is derived from "nucleus", which refers to the central part of a cell that contains genetic material. In this context, "nucleo-" specifically denotes a relationship with nucleic acids.

The suffix "-sidase" is derived from the word "hydrolase", which refers to an enzyme that catalyzes the breaking of chemical bonds using water molecules. "-Sidase" specifically indicates the hydrolysis of a specific chemical compound, in this case, nucleosides.

Combining these two components, "nucleosidase" refers to an enzyme that catalyzes the hydrolysis of nucleosides.

Plural form of NUCLEOSIDASE is NUCLEOSIDASES