How Do You Spell NUCLEOHISTON?

Pronunciation: [njˈuːklɪˌə͡ʊhɪstən] (IPA)

The word "nucleohiston" is a compound term used in biochemistry referring to a complex of DNA and histone proteins. Its spelling is derived from the combination of the words "nucleo-" referring to the cell nucleus, and "histon" referring to the protein component. It is pronounced /nju:kliəʊˈhɪstən/ in IPA phonetic transcription, with emphasis on the second syllable. The term is frequently used in genetics and molecular biology, particularly in the study of chromatin structure and gene expression.

NUCLEOHISTON Meaning and Definition

1. Nucleohistones are proteins that are found in the nucleus of cells and play a crucial role in organizing and compacting DNA. The term "nucleohiston" is a combination of two words: "nucleo," referring to the nucleus of a cell, and "histon," which refers to a group of basic proteins that tightly associate with DNA.

   Nucleohistones bind to DNA to form structures known as nucleosomes, which are fundamental units of chromatin. Chromatin is the substance that makes up the chromosomes within a cell's nucleus. Nucleohistones provide stability to the DNA molecule, as well as regulate its accessibility for various cellular processes, including gene expression and DNA replication.

   These proteins have a high content of positively charged amino acids, such as lysine and arginine, which allows them to interact with the negatively charged phosphate backbone of DNA. This interaction allows nucleohistones to coil the DNA into a compact structure and protect it from damage.

   In addition to their role in DNA compaction, nucleohistones are also involved in gene regulation. Certain modifications, such as acetylation or methylation, can alter the interactions between nucleohistones and DNA, making specific genes accessible or inaccessible to the cell's machinery. By regulating the accessibility of genes, nucleohistones play a crucial role in determining which genes are active or repressed in a given cell type or developmental stage.

   Overall, nucleohistones are vital proteins involved in maintaining the integrity and organization of DNA within the nucleus, as well as controlling the expression of genes.

2. A highly phosphorized compound of nuclein and histon present in the lymphy glands, thymus, and elsewhere.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for NUCLEOHISTON

• bucleohiston
• mucleohiston
• jucleohiston
• hucleohiston
• nycleohiston
• nhcleohiston
• njcleohiston
• nicleohiston
• n8cleohiston
• n7cleohiston
• nuxleohiston
• nuvleohiston
• nufleohiston
• nudleohiston
• nuckeohiston
• nucpeohiston
• nucoeohiston
• nuclwohiston
• nuclsohiston
• nucldohiston

Etymology of NUCLEOHISTON

The term "nucleohiston" appears to be a combination of two words: "nucleo-" and "histon".

1. "Nucleo-" is a prefix derived from the word "nucleus". In scientific contexts, it commonly refers to any structure within the cell's nucleus.

2. "Histon" refers to a group of proteins found in cell nuclei that play a crucial role in DNA packaging. These proteins combine with DNA to form complexes called nucleosomes, which further condense and wrap around to create chromatin, the material of chromosomes.

Therefore, "nucleohiston" seems to be a word combining the concepts of "nucleus" and "histon" to describe a structural or functional aspect related to nucleosomes or histones within the cell's nucleus.

Similar spelling word for NUCLEOHISTON

• nucleohistone.