How Do You Spell NUCLEIC ACID PROBES?

Pronunciation: [njuːklˈɪɪk ˈasɪd pɹˈə͡ʊbz] (IPA)

The term "nucleic acid probes" refers to short strands of nucleic acid that are used to identify and detect specific sequences of DNA or RNA. The pronunciation of this term can be broken down phonetically using the International Phonetic Alphabet (IPA) as "nu-klee-ik a-sid prohbz." Each syllable is pronounced with a clear vowel sound, and the "c" in "nucleic" is pronounced like a "k" due to the influence of the following "l" sound. The two words are pronounced separately, with stress on the second syllable of "acid."

NUCLEIC ACID PROBES Meaning and Definition

1. Nucleic acid probes are short, single-stranded fragments of DNA or RNA molecules that are used in molecular biology and genetics research to detect specific nucleotide sequences within a sample. These probes are usually labeled with a fluorescent dye or a radioactive tag, allowing the researcher to visualize and identify them in experimental assays.

   The binding specificity of nucleic acid probes relies on the complementary base-pairing principle in which adenine (A) pairs with thymine (T) in DNA or with uracil (U) in RNA, and guanine (G) pairs with cytosine (C). By designing probes with a sequence that is complementary to the target nucleic acid sequence, researchers can achieve selective hybridization and detection of the desired target.

   Nucleic acid probes are extremely versatile and have numerous applications in molecular biology and medical diagnostics. In research, they are often used for gene expression analysis, DNA sequencing, and mutation detection. Additionally, these probes can be employed in various diagnostic techniques, including fluorescence in situ hybridization (FISH) and polymerase chain reaction (PCR) assays, to detect specific pathogens, genetic disorders, or mutations associated with diseases.

   Nucleic acid probes have revolutionized the field of molecular biology, enabling scientists to target and study specific genes or nucleotide sequences with high precision. Their ability to selectively detect and bind to complementary sequences has greatly advanced our understanding of genetics and paved the way for numerous breakthroughs and discoveries in biomedical research and diagnostics.

Common Misspellings for NUCLEIC ACID PROBES

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