NORMOBLASTS Meaning and
Definition
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Normoblasts are immature red blood cells that are found in the bone marrow during the normal process of hematopoiesis, or the production of new blood cells. These cells are a distinct stage in the development of red blood cells, occurring after the formation of earlier precursor cells called proerythroblasts and erythroblasts. Normoblasts are characterized by their small size, round shape, and prominent nucleus, which occupies a significant portion of the cell.
As normoblasts undergo maturation, they gradually decrease in size and undergo changes that lead to the expulsion of their nucleus. This process allows the cell to make space for the oxygen-carrying hemoglobin molecules that fill the mature red blood cell. Once the nucleus is expelled, the cell is considered a reticulocyte, which then enters the bloodstream.
The presence of normoblasts in the peripheral blood is not typically observed in healthy individuals, as their normal development and maturation occur within the protective environment of the bone marrow. However, in certain pathological conditions, such as severe anemia or bone marrow disorders like myelodysplastic syndrome, normoblasts may be released prematurely into the bloodstream. Their appearance in the peripheral blood may indicate an abnormality in red blood cell production or maturation.
In summary, normoblasts are immature red blood cells that represent an intermediate stage in the development of erythrocytes. Their presence outside the bone marrow may signify an underlying health issue.
Common Misspellings for NORMOBLASTS
- normoblats
- normoblast
- bormoblasts
- mormoblasts
- jormoblasts
- hormoblasts
- nirmoblasts
- nkrmoblasts
- nlrmoblasts
- nprmoblasts
- n0rmoblasts
- n9rmoblasts
- noemoblasts
- nodmoblasts
- nofmoblasts
- notmoblasts
- no5moblasts
- no4moblasts
- nornoblasts
- norkoblasts
Etymology of NORMOBLASTS
The word "normoblasts" has its roots in Greek and Latin.
The term "normo-" comes from the Greek word "normos", meaning "standard" or "normal". It is often used as a prefix to indicate something that is within normal limits or conforming to a standard.
The second part of the word, "-blasts", comes from the Greek word "blastós" meaning "germ" or "bud". In medical terminology, "-blast" typically refers to an immature or developing form of a cell.
Therefore, "normoblasts" refers to a specific type of immature red blood cell that is within the normal range or conforms to the standard developmental process.
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