Nonsteroidal anti-inflammatory agents, commonly referred to as NSAIDs, are a class of medications used to reduce inflammation, relieve pain, and lower fever. They are primarily utilized in the treatment of conditions marked by inflammation, such as arthritis, but are also employed postoperatively and for other forms of acute pain management. Unlike steroidal anti-inflammatory drugs, such as corticosteroids, NSAIDs do not contain cortisone-like substances.
NSAIDs work by inhibiting the production of enzymes called cyclooxygenases (COX-1 and COX-2) in the body. These enzymes play a crucial role in the production of prostaglandins, which are hormone-like substances involved in various bodily functions, including inflammation. By blocking these enzymes, NSAIDs help to reduce inflammation, swelling, and pain.
Common examples of nonsteroidal anti-inflammatory agents include aspirin, ibuprofen, naproxen, and diclofenac. These medications are available in various forms such as tablets, capsules, gels, creams, and as injectables. Medical professionals prescribe NSAIDs by considering factors like the severity of inflammation, the individual's overall health, and potential drug interactions.
While NSAIDs are generally safe and effective when used as directed, they can be associated with certain side effects. These may include stomach ulcers, gastrointestinal bleeding, kidney problems, and an increased risk of heart problems. It is crucial to follow the recommended dosage and duration of treatment and consult with a healthcare provider if any adverse effects occur.
In summary, nonsteroidal anti-inflammatory agents are a class of medications used to reduce inflammation, relieve pain, and lower fever. They work by inhibiting the production of certain enzymes in the body, thereby reducing the production of inflammatory substances. Close monitoring and adherence
