Nodular nonsuppurative panniculitis is a medical condition characterized by the inflammation of the subcutaneous fat tissue (panniculitis) in the form of nodules that are without pus formation (nonsuppurative).
In this condition, the subcutaneous fat layer becomes inflamed due to a variety of causes, leading to the formation of firm nodules beneath the skin. These nodules typically range in size from a few millimeters to a few centimeters in diameter. The exact cause of nodular nonsuppurative panniculitis is still not fully understood, although various factors such as autoimmune reactions, infections, medications, or underlying diseases may contribute to its development.
Clinically, patients with nodular nonsuppurative panniculitis may present with symptoms such as localized pain, tenderness, redness, swelling, and occasionally, ulceration over the affected areas. The nodules can occur in any part of the body, but commonly affect the thighs, buttocks, legs, and arms.
To diagnose nodular nonsuppurative panniculitis, a healthcare professional may conduct a physical examination, review the patient's medical history, and perform various tests such as a biopsy of the affected tissue. Treatment options for this condition may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce inflammation, corticosteroids to suppress the immune response, or immunosuppressive medications to manage underlying autoimmune conditions if present. Overall, the prognosis for nodular nonsuppurative panniculitis varies depending on the underlying cause and the individual response to treatment.
