NOD MICE Meaning and
Definition
-
NOD mice, or Non-Obese Diabetic mice, are a specific strain of laboratory mice that are widely used in scientific research to study autoimmune diabetes.
These mice are characterized by their susceptibility to developing type 1 diabetes, which closely resembles the disease in humans. Unlike other strains of mice, NOD mice spontaneously develop diabetes without any external manipulation or induction. This makes them an invaluable model for studying the underlying mechanisms and potential treatments for type 1 diabetes.
NOD mice were first discovered in the late 1970s and have since been extensively studied. They have a specific genetic makeup that predisposes them to developing autoimmune diabetes. The key feature of NOD mice is their immune system's inability to properly regulate the destruction of insulin-producing cells in the pancreas. This leads to the progressive loss of insulin secretion, resulting in hyperglycemia and ultimately diabetes.
Researchers use NOD mice to understand the genetic and environmental factors that contribute to the development of type 1 diabetes. They study various aspects of the disease, such as its triggers, the immune response, and potential therapeutic interventions. NOD mice have also been instrumental in developing and testing new treatments and preventive strategies for type 1 diabetes.
Overall, NOD mice serve as an essential tool in the realm of diabetes research, providing valuable insights into the complex nature of autoimmune diabetes and aiding in the development of potential treatments and preventive measures.
Common Misspellings for NOD MICE
- bod mice
- mod mice
- jod mice
- hod mice
- nid mice
- nkd mice
- nld mice
- npd mice
- n0d mice
- n9d mice
- nos mice
- nox mice
- noc mice
- nof mice
- nor mice
- noe mice
- nod nice
- nod kice
- nod jice
- nod muce
Etymology of NOD MICE
The term "NOD mice" is derived from the acronym "NOD", which stands for "non-obese diabetic". These mice are a specific strain of laboratory mice that developed spontaneous autoimmune diabetes. The NOD mice were first discovered in Japan in the late 1970s through selective breeding for diabetes susceptibility, and they became a widely studied model for understanding the pathogenesis and treatment of type 1 diabetes. The term "NOD mice" is now commonly used in scientific research to refer to this specific strain.
Infographic
Add the infographic to your website:
