How Do You Spell NMDA RECEPTORS?

Pronunciation: [ˌɛnˌɛmdˌiːˈe͡ɪ ɹɪsˈɛptəz] (IPA)

The spelling of "NMDA receptors" can be somewhat difficult to decipher without the use of IPA phonetic transcription. IPA phonetics show that "NMDA" is pronounced as "en-em-dee-eh" and "receptors" as "ri-sep-tors." These two terms come together to form "en-em-dee-eh ri-sep-tors," which are glutamate receptors that play a key role in neural plasticity and synaptic plasticity in the brain. Proper spelling and pronunciation of medical and scientific terms are crucial in communication among researchers and healthcare professionals.

NMDA RECEPTORS Meaning and Definition

1. NMDA receptors, also known as N-methyl-D-aspartate receptors, are a specific subtype of glutamate receptors that play a crucial role in various physiological and pathological processes in the central nervous system (CNS). Glutamate is the primary excitatory neurotransmitter in the brain, and NMDA receptors are one of the major receptor types responsible for binding and detecting the presence of glutamate.

   NMDA receptors are ion channels located on the postsynaptic membranes of neurons. They are composed of multiple subunits, including the essential NR1 subunit and one or more NR2 and/or NR3 subunits. Activation of these receptors requires the binding of glutamate and the co-agonist glycine or D-serine. NMDA receptors exhibit unique properties, such as voltage-dependent magnesium block, which allows them to act as coincidence detectors of pre- and postsynaptic activity.

   Once activated, NMDA receptors allow the influx of calcium ions into the cell, which triggers a cascade of intracellular signaling pathways, leading to various physiological responses and synaptic plasticity. They are particularly important for processes like learning, memory formation, synaptic development, and synaptic plasticity. However, their dysregulation or excessive activation can also contribute to neurodegenerative disorders, stroke, epilepsy, and other pathological conditions.

   Pharmacological manipulation of NMDA receptors has been extensively studied and has led to the development of drugs targeting these receptors, such as NMDA receptor antagonists, which have therapeutic potential in conditions involving excessive glutamate release or NMDA receptor hyperactivity.

Common Misspellings for NMDA RECEPTORS

• bmda receptors
• mmda receptors
• jmda receptors
• hmda receptors
• nnda receptors
• nkda receptors
• njda receptors
• nmsa receptors
• nmxa receptors
• nmca receptors
• nmfa receptors
• nmra receptors
• nmea receptors
• nmdz receptors
• nmds receptors
• nmdw receptors
• nmdq receptors
• nmda eeceptors
• nmda deceptors
• nmda feceptors

Etymology of NMDA RECEPTORS

The word "NMDA receptors" is an acronym for N-Methyl-D-Aspartate receptors. The etymology of this term can be traced back to the components of the acronym:

- N: Refers to N-Methyl, which signifies the substitution of a methyl (-CH3) group to a nitrogen atom in the chemical structure.

- M: Represents Methyl, a chemical group consisting of one carbon atom bonded to three hydrogen atoms (-CH3).

- D: Stands for D-Aspartate, an enantiomer of the amino acid aspartate. The "D" designation refers to its configuration in the molecule.

- A: Represents Aspartate, an amino acid that is one of the building blocks of proteins.

Therefore, NMDA receptors are named after the specific ligand or molecule, N-Methyl-D-Aspartate, that binds to and activates these receptors in the brain.