Nisoldipine is a medication used to treat high blood pressure. Its name is derived from a combination of its chemical components: N-isopropyl, N-ethyl, and dihydropyridine. The IPA phonetic transcription for this word is /nɪˈsɒldɪpaɪn/. The stress falls on the second syllable, and it is pronounced with a short "i" sound at the beginning followed by an "s" sound. The final syllable ends with a diphthong sound made by the combination of the letter "i" and the letter "n".
Nisoldipine is a noun that refers to a prescription medication used to treat high blood pressure (hypertension). It falls into the category of medications known as calcium channel blockers.
In terms of its chemical structure, nisoldipine is a dihydropyridine derivative with a pyridine ring and a nitro functionality. It works by blocking the influx of calcium ions into smooth muscle cells of the blood vessels, thereby reducing the overall effect of calcium on muscle contraction. This relaxation of the blood vessels results in a decrease in systemic vascular resistance and subsequently helps to lower blood pressure.
Nisoldipine comes in the form of oral extended-release tablets, with different strengths available depending on individual patient needs. The medication is typically taken once daily, preferably on an empty stomach or as directed by a healthcare professional. It is essential to follow the prescribed dosage regimen and not to crush or break the tablets before ingestion.
As with most medications, there are potential side effects associated with nisoldipine. These can include but are not limited to flushing, headache, dizziness, swelling in the ankles or feet, and changes in heart rate. It is important for patients to consult with their doctor if they experience severe or persistent side effects while taking nisoldipine.
Overall, nisoldipine is a calcium channel blocker prescribed to help manage hypertension and reduce the risk of related complications such as heart disease or stroke.