NGAL Meaning and
Definition
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NGAL, short for Neutrophil Gelatinase-Associated Lipocalin, is a protein biomarker that plays a crucial role in various biological processes. It is primarily secreted by neutrophils and other immune cells in response to inflammation and infection. NGAL is found in various bodily fluids, including blood, urine, and cerebrospinal fluid.
In the context of medical diagnosis, NGAL has gained significant attention as it is associated with acute kidney injury (AKI) and chronic kidney disease (CKD). Increased levels of NGAL in the urine or blood can indicate early signs of kidney dysfunction, making it a valuable tool for the timely detection and monitoring of these conditions. Additionally, NGAL has been found to be a useful biomarker in guiding the risk assessment and treatment of cardiac diseases, sepsis, and other critical illnesses.
Apart from its clinical applications, NGAL also has physiological roles in iron metabolism, cellular growth, and the protection against bacterial infections. Its ability to bind to bacterial siderophores helps to maintain a balanced iron homeostasis in the body.
Overall, NGAL is a versatile protein biomarker that has proven to be of great significance in the field of medicine. Its clinical applications extend beyond kidney disease, making it a valuable tool for diagnosing and managing various inflammatory and infectious conditions. Further research on NGAL's mechanisms and therapeutic potential is likely to uncover more insights into its multifaceted roles in human health and disease.
Common Misspellings for NGAL
- ngzl
- nbgal
- mngal
- nmgal
- njgal
- hngal
- ngbal
- ngyal
- ntgal
- ngzal
- ngazl
- ngsal
- ngasl
- ngwal
- ngawl
- ngqal
- ngaql
- ngakl
- ngalk
- ngapl
- ngalp
- ngalo
- nggal
- ngaal
- n gal
- ng al
- nga l
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