The word "neurolemma" is spelled with six syllables, with the primary stress on the second syllable. It is pronounced n(y)oo-rə-LEM-ə, with the first syllable being the SCHWA sound (ə) and the third syllable featuring an E sound like "bet" (LEM). The term is used to describe the outermost layer of a nerve fiber, which is composed of Schwann cells. It serves as a protective sheath for the nerve fiber, allowing for proper nerve function and communication throughout the body.
The term "neurolemma" refers to the outermost layer of a nerve fiber, also known as the sheath of Schwann. It is a critical component of the peripheral nervous system (PNS) and plays a crucial role in nerve regeneration and protection. The neurolemma primarily consists of Schwann cells – specialized glial cells that wrap themselves in multiple layers around nerve fibers.
The neurolemma performs several essential functions. Firstly, it provides structural integrity to nerve fibers, serving as a protective covering that helps prevent damage and maintain the integrity of the axons within. Secondly, it facilitates nerve repair and regeneration by creating a conducive environment for regrowth. Schwann cells within the neurolemma release growth factors and guidance molecules that aid in directing regenerating axons back to their original targets.
Another significant role of the neurolemma is its involvement in the process of myelination. Schwann cells form individual myelin sheaths by wrapping around segments of the nerve fiber. This myelin sheath helps enhance the conduction velocity of nerve impulses along the fiber, resulting in faster and more efficient signaling.
Overall, the neurolemma is a crucial component of peripheral nerve fibers, providing support, protection, and assistance in regeneration. Its involvement in myelination and nerve repair makes it an essential structure for the proper functioning of the peripheral nervous system.
An old term for the retina; not to be confused with neurilemma.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "neurolemma" comes from the combination of two Greek roots: "neuro" meaning "nerve" and "lemma" meaning "sheath". The term was coined in the mid-19th century to refer to the outermost covering of nerve fibers, which is also known as the "perineurium". This protective sheath plays a crucial role in maintaining and supporting nerve function.