NEBULIN Meaning and
Definition
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Nebulin is a noun that refers to a protein found in skeletal muscles, particularly in the thin filaments of sarcomeres. It is a large protein molecule that plays a crucial role in muscle function and structure. Nebulin is primarily found in vertebrates, including humans.
Structurally, nebulin consists of a long polypeptide chain, and its length is directly proportional to the size of the sarcomeres it is present in. This protein plays a vital role in regulating muscle contraction and maintaining the overall stability of the sarcomeres.
Nebulin is involved in the assembly and alignment of actin filaments within the muscle sarcomeres. It acts as a template during the formation of new actin filaments and also helps to regulate the length of these filaments. By doing so, nebulin contributes to the overall architecture and functioning of skeletal muscles.
Mutations in the gene that encodes nebulin have been linked to various muscle diseases, including nemaline myopathy, a congenital disorder characterized by muscle weakness and reduced muscle tone. These mutations affect the structure and function of nebulin, disrupting the normal assembly and regulation of muscle fibers.
In summary, nebulin is a protein present in skeletal muscles. It contributes to the assembly and alignment of actin filaments within muscle sarcomeres, playing a crucial role in muscle contraction and stability.
Common Misspellings for NEBULIN
- bebulin
- mebulin
- jebulin
- hebulin
- nwbulin
- nsbulin
- ndbulin
- nrbulin
- n4bulin
- n3bulin
- nevulin
- nenulin
- nehulin
- negulin
- nebylin
- nebhlin
- nebjlin
- nebilin
- neb8lin
- neb7lin
Etymology of NEBULIN
The word "nebulin" has a scientific origin and its etymology can be traced back to the realm of biology, particularly genetics and molecular biology.
The term "nebulin" was coined by the American biochemist Roger Craig in 1971. It was derived from the word "nebula", which means a cloud of gas and dust in space. Craig chose this name because it reflects the appearance of nebulin, a large filamentous protein found in skeletal muscles.
Nebulin is known for its role in muscle contraction. It is a structural component of the thin filament in skeletal muscle fibers, which interact with thick filaments (composed of myosin) to generate muscle contraction. Nebulin helps maintain the precise structure and length of the thin filament, playing a crucial role in muscle function.
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