Native albumin refers to the naturally occurring form of a protein known as albumin. Albumin is the most abundant protein in blood plasma and is synthesized by the liver. It is responsible for numerous critical physiological functions in the body.
Native albumin is primarily found in its natural state before any chemical modifications or alterations occur. It is characterized by its specific molecular structure and properties. Native albumin molecules are composed of a single polypeptide chain with multiple subunits, creating a globular shape. These subunits are held together by chemical bonds, ensuring the stability and integrity of the protein.
As a carrier protein, native albumin plays a crucial role in the transport of various substances, such as hormones, fatty acids, vitamins, and drugs, throughout the bloodstream. It helps maintain osmotic pressure, regulating the distribution of fluids between blood vessels and tissues. Additionally, native albumin participates in buffering pH levels and acts as an antioxidant, protecting cells from oxidative damage.
Various medical and research applications utilize native albumin. It serves as a benchmark for the determination of albumin levels in clinical blood tests. It also serves as a reference protein to assess protein stability and drug-protein interactions during scientific studies. Additionally, native albumin plays a significant role in therapeutic treatments, including intravenous administration for fluid replacement or as a carrier for drugs or treatment molecules.
Overall, native albumin is the unmodified, naturally occurring form of the protein albumin found in blood plasma, showcasing vital functions for the normal functioning of the human body.
