How Do You Spell NALORPHINE?

Pronunciation: [nˈalɔːfˌiːn] (IPA)

The word "nalorphine" is spelled as "næˈlɔrfin." It is a narcotic antagonist that has been used to alleviate pain, but its use has been discontinued due to its side effects. The spelling of the word follows the International Phonetic Alphabet, which represents the sounds of the word. The first syllable is pronounced as "næ," pronounced with an open front vowel like "cat." The second syllable is pronounced as "lɔr," where the "ɔ" is pronounced like "caught." The final syllable "-fin" is pronounced with an "in" sound.

NALORPHINE Meaning and Definition

1. Nalorphine is a synthetic opioid drug that belongs to the category of narcotic antagonists. It is primarily used for its antagonistic properties, meaning it blocks the effects of opiate drugs like heroin or morphine. Nalorphine acts by binding to and occupying opioid receptors in the brain, thereby preventing other opioid drugs from attaching to these receptors, and consequently, counteracting their effects. It is often used in medical settings to reverse the effects of opioid overdose or to diagnose and treat opioid dependence.

   As a partial opioid antagonist, nalorphine has a lower affinity for opioid receptors compared to full opioid agonists like morphine, resulting in a reduced risk of respiratory depression and sedation. However, nalorphine can still trigger a withdrawal syndrome in individuals who are opioid-dependent, making it an effective tool for the diagnosis of opioid addiction.

   Nalorphine was first synthesized in the 1940s and was notably used in the treatment of opioid dependence before the development of other more potent and safer medications, such as methadone or buprenorphine. Its use has become less common in recent years due to its limited efficacy and the availability of alternative medications with more favorable safety profiles. Nonetheless, nalorphine continues to be used in certain cases, particularly in emergency medical situations where the reversal of opioid overdose is required.

Common Misspellings for NALORPHINE

• balorphine
• malorphine
• jalorphine
• halorphine
• nzlorphine
• nslorphine
• nwlorphine
• nqlorphine
• nakorphine
• naporphine
• naoorphine
• nalirphine
• nalkrphine
• nallrphine
• nalprphine
• nal0rphine
• nal9rphine
• naloephine
• nalodphine

Etymology of NALORPHINE

The word "nalorphine" is derived from "N-allyl-" and "morphine".

"N-allyl" refers to the N-allyl substitution on the morphine molecule, which means an allyl group (-CH2CH=CH2) is attached to the nitrogen atom of the morphine structure. This modification changes the pharmacological properties of the compound.

"Morphine" refers to the opiate alkaloid derived from the opium poppy plant. The name "morphine" is attributed to its ability to induce sleep and the Greek god of dreams, Morpheus. It was first isolated from opium in the early 19th century and is known for its potent analgesic (pain-relieving) properties.

Combining these two elements, "nalorphine" represents a compound with an allyl substitution on the morphine structure.

Plural form of NALORPHINE is NALORPHINES