NALIDIXIN Meaning and
Definition
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Nalidixin is a synthetic antibacterial agent belonging to the class of quinolone antibiotics. It is derived from nalidixic acid and possesses a broad spectrum of activity against both gram-positive and gram-negative bacteria. Nalidixin is usually administered orally and is used primarily to treat urinary tract infections caused by susceptible microorganisms.
The mechanism of action of nalidixin involves inhibition of bacterial DNA replication by targeting the enzyme DNA gyrase, thus preventing the synthesis and repair of DNA. This disruption of DNA function leads to bacterial cell death and effectively controls the growth and spread of the infection.
Nalidixin is generally well tolerated, with adverse effects being relatively rare. However, some individuals may experience gastrointestinal disturbances such as nausea, vomiting, abdominal pain, or diarrhea. In rare cases, more severe side effects like allergic reactions or liver dysfunction may occur, requiring immediate medical attention.
It is important to note that nalidixin is not effective against all types of bacterial infections. Its use should be guided by susceptibility testing to ensure appropriate treatment. Additionally, nalidixin is not meant for the treatment of viral or fungal infections.
Overall, nalidixin is a potent antibiotic that effectively targets and inhibits bacterial DNA replication, making it a valuable tool in the treatment of urinary tract infections caused by susceptible bacteria.
Common Misspellings for NALIDIXIN
- balidixin
- malidixin
- jalidixin
- halidixin
- nzlidixin
- nslidixin
- nwlidixin
- nqlidixin
- nakidixin
- napidixin
- naoidixin
- naludixin
- naljdixin
- nalkdixin
- nalodixin
- nal9dixin
- nal8dixin
- nalisixin
- nalixixin
- nalicixin
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