Myleran, also known by its generic name busulfan, is a chemotherapy drug belonging to the class of alkylating agents. It is primarily used to treat different types of cancer, including chronic myelogenous leukemia (CML), polycythemia vera, and essential thrombocythemia.
Myleran is classified as a bifunctional alkylating agent because it works by binding to the DNA molecule and forming crosslinks between the DNA strands, which interfere with DNA replication and synthesis. This action prevents cancer cells from dividing and growing, ultimately leading to their death.
The medication is available in different forms, including tablets and oral powder, and is usually taken by mouth. It is typically prescribed as a long-term treatment, often in combination with other anticancer drugs, and requires close monitoring by a healthcare professional.
Common side effects of Myleran may include nausea, vomiting, diarrhea, mouth sores, skin rash, thinning of the hair, and changes in the color of the skin or nails. It can also cause bone marrow suppression, resulting in decreased production of red and white blood cells and platelets.
Due to its potential toxic effects, Myleran should only be used under the supervision of a healthcare provider experienced in prescribing chemotherapy drugs. Patients are advised to follow the prescribed dosage and schedule carefully and report any unusual side effects promptly.
