MYC ONCOGENE Meaning and
Definition
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The term "MYC oncogene" refers to a specific gene that is associated with the development and progression of cancer. It is an oncogene, which means it has the potential to induce the formation of tumors when its normal regulatory processes are disrupted.
The MYC oncogene is a member of the MYC family of proto-oncogenes, which also includes the MYCN and MYCL genes. These genes play crucial roles in the regulation of cell division, growth, and differentiation. When the MYC oncogene is activated or overexpressed due to genetic mutations or amplification, it can lead to uncontrolled cell proliferation and the formation of malignant tumors.
The MYC oncogene encodes a transcription factor protein known as c-Myc, which binds to specific DNA sequences and regulates the expression of numerous genes involved in cell cycle progression, metabolism, and apoptosis. Dysregulation of these genes can result in abnormal cell growth and survival, contributing to the development of cancer.
The MYC oncogene has been implicated in various types of cancers, including hematological malignancies (such as leukemia and lymphoma) as well as solid tumors (such as breast, lung, and colon cancers). Its involvement in cancer progression makes the MYC oncogene an attractive target for therapeutic interventions and drug development.
In summary, the MYC oncogene is a gene that, when inappropriately activated, can contribute to the development and progression of cancer by promoting cell proliferation and survival.
Common Misspellings for MYC ONCOGENE
- nyc oncogene
- kyc oncogene
- jyc oncogene
- mtc oncogene
- mgc oncogene
- mhc oncogene
- muc oncogene
- m7c oncogene
- m6c oncogene
- myx oncogene
- myd oncogene
- myc incogene
- myc kncogene
- myc lncogene
- myc pncogene
- myc 0ncogene
- myc 9ncogene
- myc obcogene
- myc omcogene
- myc ojcogene
Etymology of MYC ONCOGENE
The term "myc oncogene" is derived from two sources: "myc" and "oncogene".
1. "Myc": The term "myc" originates from the c-Myc protein, which is a transcription factor involved in the regulation of cell growth and proliferation. The c-Myc protein is encoded by the MYC gene. The name "Myc" was coined by the scientists J. Michael Bishop and Harold Varmus, who discovered the association between the myc gene and cancer development in the 1970s.
2. "Oncogene": The term "oncogene" is a combination of two Greek words, "onkos" meaning "mass" or "bulk" and "gene" meaning "origin" or "birth". It was first introduced by German virologist Peyton Rous in 1911 to describe genes present in cancer-causing viruses.
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