MOUSE CYTOMEGALOVIRUS Meaning and
Definition
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Mouse Cytomegalovirus (MCMV) is a species-specific virus that belongs to the family Herpesviridae and the Betaherpesvirinae subfamily. It is a DNA virus that primarily infects mice and serves as an important model for studying human cytomegalovirus (HCMV) and related diseases. MCMV is commonly used in scientific research to investigate viral pathogenesis, immune responses, and the development of therapeutic interventions for human cytomegalovirus infections.
MCMV is characterized by its ability to establish lifelong latent infections in mice, with intermittent reactivations in immunocompromised individuals. It can be transmitted horizontally through contact with infected secretions, primarily saliva, urine, and reproductive fluids. Vertical transmission from mother to offspring can also occur during pregnancy or through lactation.
In mice, MCMV infection can result in a spectrum of outcomes, ranging from asymptomatic or mild disease to severe and lethal infections. The virus has a broad tissue tropism, with the ability to infect and replicate in various cell types, including epithelial, endothelial, and immune cells. MCMV infection can lead to multiple clinical manifestations, such as hepatomegaly, splenomegaly, pneumonitis, and hepatitis, depending on the strain of the virus and the immune status of the host.
Studying MCMV infection provides insights into the molecular mechanisms of viral replication, immune evasion strategies, and host responses. It serves as a useful model to explore the interplay between viral pathogens and the immune system, aiding in the development of vaccines and antiviral therapies against cytomegalovirus infections in humans.
Common Misspellings for MOUSE CYTOMEGALOVIRUS
- nouse cytomegalovirus
- kouse cytomegalovirus
- jouse cytomegalovirus
- miuse cytomegalovirus
- mkuse cytomegalovirus
- mluse cytomegalovirus
- mpuse cytomegalovirus
- m0use cytomegalovirus
- m9use cytomegalovirus
- moyse cytomegalovirus
- mohse cytomegalovirus
- mojse cytomegalovirus
- moise cytomegalovirus
- mo8se cytomegalovirus
- mo7se cytomegalovirus
- mouae cytomegalovirus
- mouze cytomegalovirus
- mouxe cytomegalovirus
- moude cytomegalovirus
- mouee cytomegalovirus
Etymology of MOUSE CYTOMEGALOVIRUS
The word "Mouse Cytomegalovirus" has its origins in the fields of virology and microbiology. Let's break down the etymology of this term:
1. Mouse: The term "mouse" refers to the small mammalian rodent belonging to the family Muridae. It comes from the Old English word "mus" and can be traced back to Proto-Germanic roots.
2. Cytomegalovirus: "Cytomegalovirus" is a compound word derived from the combination of three terms: "cyto-" meaning cell, "mega-" meaning large, and "virus" referring to an infectious agent.
- Cytomegalovirus: The term "cytomegalovirus" itself originated from the Greek words "kytos" meaning cell, "megas" meaning large, and "virus".
