The spelling of the word "most tissued" can be tricky, as it can be parsed as two separate words. However, it is actually one compound word, pronounced as /məʊst ˈtɪʃuːd/. The first syllable is pronounced like "moat" and the second syllable rhymes with "issued". The word means "most adorned with tissue paper," and its unique spelling reflects its origins in the world of gift wrapping and decoration. Despite its relatively obscure usage, "most tissued" is a valid compound word with a clear pronunciation.