Most disentranced is spelled /moʊst dɪsɪnˈtrænst/. The word "most" is pronounced with the long "o" sound /moʊst/, while the word "disentranced" is pronounced with the schwa sound in the second syllable /dɪsɪnˈtrænst/. The prefix "dis-" means the opposite of, and "entranced" means captivated or fascinated. Therefore, "most disentranced" means the least captivated or fascinated, as in being unimpressed or bored. This word is a rare and unusual combination of words, but it can be used to describe a lack of interest in something.