MONODEIODINASE Meaning and
Definition
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Monodeiodinase is an enzyme that is involved in the biological conversion and regulation of thyroid hormones in living organisms. Specifically, it catalyzes the removal of iodine from iodinated thyronines, a process known as deiodination. This enzyme is responsible for the deiodination of the prohormone thyroxine (T4) to the active hormone triiodothyronine (T3). This conversion enhances the biological activity of thyroid hormones, as T3 is the more potent form that exerts its effects on various tissues and cells.
Monodeiodinase is found in several tissues and organs, including the liver, kidney, skeletal muscle, and brain. It plays a crucial role in maintaining thyroid hormone homeostasis and regulating metabolic processes in the body. Through this enzyme, the conversion of T4 to T3 is tightly regulated, ensuring the adequate supply of active thyroid hormone when needed.
The activity of monodeiodinase can be influenced by various factors, such as hormonal signals, nutritional status, and environmental factors. Dysregulation or dysfunction of this enzyme can lead to thyroid disorders, including hypothyroidism or hyperthyroidism. Therefore, monodeiodinase is an essential enzyme in thyroid hormone metabolism and has significant implications in maintaining overall physiological balance in organisms.
Common Misspellings for MONODEIODINASE
- nonodeiodinase
- konodeiodinase
- jonodeiodinase
- minodeiodinase
- mknodeiodinase
- mlnodeiodinase
- mpnodeiodinase
- m0nodeiodinase
- m9nodeiodinase
- mobodeiodinase
- momodeiodinase
- mojodeiodinase
- mohodeiodinase
- monideiodinase
- monkdeiodinase
- monldeiodinase
- monpdeiodinase
- mon0deiodinase
- mon9deiodinase
- monoseiodinase
Etymology of MONODEIODINASE
The word "monodeiodinase" is derived from the combination of three components: "mono", "de", and "iodinase".
1. "Mono" is a prefix derived from the Greek word "monos", meaning "single" or "alone". It is used to indicate the presence of one or a single entity.
2. "De" is a prefix taken from the Latin word "de", meaning "remove" or "undo". It is typically used to indicate the removal of something or the reversal of a process.
3. "Iodinase" is a term derived from the word "iodine", which is a chemical element in the periodic table. It refers to enzymes that catalyze the cleavage or rearrangement of iodine-containing compounds.
Therefore, when combined, "monodeiodinase" refers to an enzyme that removes or alters a single iodine atom in a molecule.
