How Do You Spell METHYLMALONYL COA ISOMERASE?

Pronunciation: [mˈiːθɪlmˌalənˌa͡ɪl kˈə͡ʊ ɐ ˈa͡ɪsə͡ʊmɹˌe͡ɪz] (IPA)

Methylmalonyl CoA Isomerase is an enzyme that plays a crucial role in cellular metabolism. The word "methylmalonyl" is pronounced /mɛθəlməlɒnəl/, with the stress on the second syllable. "CoA" is pronounced as /koʊeɪ/ and "isomerase" is pronounced as /aɪˈsɒməreɪz/. The word "isomerase" refers to an enzyme that catalyzes the conversion of a molecule into its isomer. In this case, Methylmalonyl CoA Isomerase converts methylmalonyl-CoA to succinyl-CoA, an essential step in the metabolism of amino acids and fatty acids.

Meaning and Definition
Common Misspellings
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METHYLMALONYL COA ISOMERASE Meaning and Definition

  1. Methylmalonyl CoA isomerase is an enzyme that plays a crucial role in the metabolism of certain organic compounds in living organisms. Specifically, it catalyzes the reversible isomerization of methylmalonyl CoA into succinyl CoA. This reaction is an essential step in the breakdown of branched-chain amino acids and fatty acids with odd numbers of carbon atoms.

    Methylmalonyl CoA isomerase is found in various tissues, including the liver, kidneys, and muscles, where it participates in the metabolism of certain nutrients. Its function is particularly important in individuals with inherited disorders known as methylmalonic aciduria, in which the enzyme is deficient or non-functional. In these cases, the accumulation of methylmalonic acid in the body can lead to severe metabolic disturbances and various health complications.

    The enzyme itself is a protein composed of amino acids, and its activity is dependent on the presence of certain cofactors, such as biotin. Through a complex biochemical process, methylmalonyl CoA isomerase facilitates the rearrangement of chemical bonds within the substrate molecule, resulting in the formation of succinyl CoA.

    Overall, the function of methylmalonyl CoA isomerase is vital for proper metabolism and energy production in living organisms. Its activity allows for the efficient breakdown of specific molecules, ensuring the availability of essential intermediates for various biochemical pathways.

Common Misspellings for METHYLMALONYL COA ISOMERASE

  • nethylmalonyl coa isomerase
  • kethylmalonyl coa isomerase
  • jethylmalonyl coa isomerase
  • mwthylmalonyl coa isomerase
  • msthylmalonyl coa isomerase
  • mdthylmalonyl coa isomerase
  • mrthylmalonyl coa isomerase
  • m4thylmalonyl coa isomerase
  • m3thylmalonyl coa isomerase
  • merhylmalonyl coa isomerase
  • mefhylmalonyl coa isomerase
  • meghylmalonyl coa isomerase
  • meyhylmalonyl coa isomerase
  • me6hylmalonyl coa isomerase
  • me5hylmalonyl coa isomerase
  • metgylmalonyl coa isomerase
  • metbylmalonyl coa isomerase
  • metnylmalonyl coa isomerase
  • metjylmalonyl coa isomerase
  • metuylmalonyl coa isomerase