The correct spelling of "methylene hippuric acid" can be a bit tricky as it involves a few uncommon letter combinations. It is pronounced as /məˈθaɪlin hɪˈpjʊərɪk ˈæsɪd/ using the IPA phonetic transcription. The "methylene" part is spelled with a "y" to represent the "i" sound, while the "hippuric acid" part is spelled with a double "p" to indicate the stress on the second syllable. Remembering these details can help ensure proper spelling and pronunciation of this scientific term.
Methylene hippuric acid, also known as N-methylhippuric acid or benzoylglycine, is a chemical compound derived from the metabolism of toluene. It is classified as a urinary metabolite since it is primarily excreted in the urine.
Chemically, methylene hippuric acid is an N-alkyl-substituted derivative of hippuric acid, with a methyl group attached to the nitrogen atom. The compound is formed when toluene is metabolized in the liver through a series of oxidation reactions. Methylene hippuric acid is the major metabolite of toluene, and its presence in urine is often used as an indicator of exposure to this organic solvent.
In terms of its significance, the detection of methylene hippuric acid in urine can provide valuable information regarding occupational or environmental exposure to toluene. This compound serves as a biomarker or indicator of toluene exposure, helping to assess levels of exposure and evaluate the potential health risks associated with it. Urinary analysis for methylene hippuric acid is commonly employed as a non-invasive method for monitoring toluene exposure in industries where toluene is used, such as the chemical, paint, and printing industries.
In summary, methylene hippuric acid is a metabolite produced during the breakdown of toluene in the liver. Its presence in urine serves as an important indicator of exposure to toluene, providing insights into potential health risks associated with this organic solvent.
Hippol.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.