METASTASIS SUPPRESSOR GENE Meaning and
Definition
-
Metastasis Suppressor Gene: A metastasis suppressor gene is a type of gene that plays a crucial role in preventing or inhibiting the spread (metastasis) of cancerous cells from their original site to other locations in the body. These genes act as a barrier against the aggressive behavior of cancer cells and work to maintain normal cell functioning and tissue integrity.
Metastasis suppressor genes encode proteins that regulate various cellular processes involved in cancer metastasis. These processes include cell adhesion, cell migration, invasion, angiogenesis (formation of new blood vessels), and immune response. The proteins produced by these genes can directly or indirectly inhibit these processes, preventing the cancer cells from breaking free from the primary tumor, entering the bloodstream or lymphatic system, and colonizing distant organs or tissues.
Unlike oncogenes, which promote tumor growth and metastasis, metastasis suppressor genes act as tumor suppressors. Mutations or alterations in these genes can result in a loss of their suppressive functions, leading to enhanced metastatic potential of cancer cells.
Scientists actively study metastasis suppressor genes to understand their mechanisms of action and identify potential therapeutic targets for preventing or treating cancer metastasis. By manipulating these genes or their related pathways, researchers aim to develop targeted therapies that can block the spread of cancer cells, improve patient outcomes and minimize the risk of cancer recurrence.
Common Misspellings for METASTASIS SUPPRESSOR GENE
- m etastasis suppressor gene
- me tastasis suppressor gene
- met astasis suppressor gene
- meta stasis suppressor gene
- metas tasis suppressor gene
- metast asis suppressor gene
- metasta sis suppressor gene
- metastas is suppressor gene
- metastasi s suppressor gene
- metastasis s uppressor gene
- metastasis suppr essor gene
- metastasis suppre ssor gene
- metastasis suppres sor gene
- metastasis suppress or gene
- metastasis suppresso r gene
- metastasis suppressor g ene
- metastasis suppressor ge ne
- metastasis suppressor gen e
