MESANGIOCAPILLARY GLOMERULONEPHRITIS Meaning and
Definition
-
Mesangiocapillary glomerulonephritis (also known as membranoproliferative glomerulonephritis or MPGN) is a rare type of kidney disease that primarily affects the glomeruli, which are the tiny blood vessels in the kidneys responsible for filtering waste and excess fluids from the blood.
In mesangiocapillary glomerulonephritis, the glomeruli become inflamed, leading to damage and scarring. This inflammation is often caused by the abnormal accumulation of immune complexes, which are clusters of antibodies and antigens that mistakenly attack the healthy tissues in the kidneys.
The condition is characterized by a thickening of the glomerular basement membrane and the proliferation of mesangial cells, which are the specialized cells that support the structure of the glomeruli. This abnormal thickening and cell growth impair the proper filtration of blood and the excretion of waste products, leading to a buildup of toxins and fluids in the body.
The symptoms of mesangiocapillary glomerulonephritis can vary but often include blood in the urine (hematuria), proteinuria (excess protein in the urine), high blood pressure, swelling in the legs and ankles (edema), fatigue, and decreased urine output. If left untreated, the disease can progress and cause chronic kidney failure, potentially requiring dialysis or a kidney transplant.
The exact cause of mesangiocapillary glomerulonephritis is often unknown, but it can be associated with certain infections, autoimmune disorders, or inherited conditions. Treatment options typically focus on managing the symptoms, controlling blood pressure, and reducing inflammation. Immunosuppressive medications may also be prescribed to suppress the immune system's response and slow down the progression of the disease.
Common Misspellings for MESANGIOCAPILLARY GLOMERULONEPHRITIS
- nesangiocapillary glomerulonephritis
- kesangiocapillary glomerulonephritis
- jesangiocapillary glomerulonephritis
- mwsangiocapillary glomerulonephritis
- mssangiocapillary glomerulonephritis
- mdsangiocapillary glomerulonephritis
- mrsangiocapillary glomerulonephritis
- m4sangiocapillary glomerulonephritis
- m3sangiocapillary glomerulonephritis
- meaangiocapillary glomerulonephritis
- mezangiocapillary glomerulonephritis
- mexangiocapillary glomerulonephritis
- medangiocapillary glomerulonephritis
- meeangiocapillary glomerulonephritis
- mewangiocapillary glomerulonephritis
- meszngiocapillary glomerulonephritis
- messngiocapillary glomerulonephritis
- meswngiocapillary glomerulonephritis
- mesqngiocapillary glomerulonephritis
- mesabgiocapillary glomerulonephritis
Etymology of MESANGIOCAPILLARY GLOMERULONEPHRITIS
The word "mesangiocapillary glomerulonephritis" is derived from several Greek and Latin roots.
1. "Mesangio" comes from the Greek word "mesos", meaning "middle", and "aggeion", meaning "vessel". It refers to the mesangium, which is the middle layer of cells in the glomerulus of the kidney.
2. "Capillary" is derived from the Latin word "capillaris", which means "hair-like". It denotes the small, thin-walled blood vessels found in the glomerulus.
3. "Glomerulonephritis" is a combination of the Latin word "glomerulus", meaning "small ball", and the Greek word "nephros", meaning "kidney". It refers to the inflammation of the glomerulus in the kidney.
