MEGLITINIDE Meaning and
Definition
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Meglitinides are a class of oral antidiabetic medications that are primarily used for the management of type 2 diabetes mellitus. These drugs work by stimulating the release of insulin from the pancreatic beta cells, which helps to lower blood glucose levels.
Meglitinides, also known as meglitinide analogs or glinides, function by binding to and activating a specific receptor known as the ATP-sensitive potassium channel on the surface of the beta cells in the pancreas. This mechanism of action promotes the influx of calcium ions into the beta cells, triggering the release of insulin into the bloodstream.
These drugs have a rapid onset of action, allowing them to effectively control postprandial hyperglycemia (high blood sugar levels after meals). Meglitinides are typically taken before meals, with the dosage adjusted based on the anticipated carbohydrate intake. Due to their short duration of action, these medications have a lower risk of causing hypoglycemia (low blood sugar) compared to other antidiabetic medications.
Commonly used meglitinides include repaglinide and nateglinide. Repaglinide is taken before each meal and is rapidly absorbed, exhibiting its peak effect within an hour after intake. Nateglinide is also taken before meals but has a slightly slower onset and a longer duration of action compared to repaglinide.
In summary, meglitinides are a class of oral antidiabetic medications that stimulate insulin release from pancreatic beta cells, effectively controlling blood glucose levels in individuals with type 2 diabetes.
Common Misspellings for MEGLITINIDE
- neglitinide
- keglitinide
- jeglitinide
- mwglitinide
- msglitinide
- mdglitinide
- mrglitinide
- m4glitinide
- m3glitinide
- meflitinide
- mevlitinide
- meblitinide
- mehlitinide
- meylitinide
- metlitinide
- megkitinide
- megpitinide
- megoitinide
- meglutinide
- megljtinide
Etymology of MEGLITINIDE
The word "meglitinide" is a combination of two components: "meglit-" and "-nide".
The "meglit-" portion of the word is derived from "meglitin", which refers to a class of drugs used in the treatment of type 2 diabetes. These drugs work by stimulating the release of insulin from the pancreas, helping to lower blood sugar levels.
The "-nide" suffix is a commonly used suffix in chemistry and pharmacology to denote certain groups of compounds or functional groups.
Therefore, "meglitinide" can be understood as a term used to describe a specific class of drugs (meglitins) with a particular pharmacological action (-nide).
