The spelling of the word "mcquain" can be confusing due to the irregular way the letters are arranged. Using IPA phonetic transcription can help to clarify the pronunciation of this word. It can be written as /məkweɪn/, with the accent on the second syllable. The "mc" is pronounced as one sound, "mək", followed by the "w" and "a" sounds in quick succession. The final "in" is pronounced as "ɪn", making the word "mcquain" sound like mək-weyn.