McKendree is a surname commonly found in the United States. It is pronounced as /makɛnˈdri/ in IPA phonetic transcription. The spelling of the name can be broken down into three parts: "Mc" which is a prefix of Scottish or Irish origin meaning "son of"; "Ken" which is a Gaelic name meaning "handsome"; and "dree" which is a Scottish word meaning "sorcery" or "witchcraft". The spelling of the name is a unique combination that reflects its ancestry and history.