Masked gout is a medical condition characterized by atypical, non-articular manifestations of gout, which can make its diagnosis and identification more challenging. Gout itself is a type of inflammatory arthritis caused by the presence of excessive uric acid in the body, resulting in the formation of urate crystals in the joints. However, masked gout presents with symptoms that are not commonly associated with the classic picture of gout.
In masked gout, the characteristic acute joint pain and swelling seen in regular gout attacks may be absent or less prominent. Instead, individuals with masked gout often experience symptoms such as fatigue, low-grade fever, systemic inflammation, and various organ-specific manifestations, including kidney stones or renal impairment, cardiovascular abnormalities, fatty liver disease, or even certain skin conditions.
Due to the atypical nature of these symptoms, masked gout is often misdiagnosed or overlooked, leading to delayed or inadequate treatment. It is important for healthcare professionals to remain vigilant when evaluating patients with unexplained systemic symptoms, as prompt recognition of masked gout can prevent long-term complications and improve patient outcomes.
Diagnosis of masked gout typically involves a thorough medical history, physical examination, and laboratory tests to measure serum uric acid levels and exclude other possible causes of the symptoms. Once identified, treatment options for masked gout usually include medications to lower uric acid levels, manage inflammation, and address any associated comorbidities. Additionally, lifestyle modifications such as dietary changes and maintaining a healthy weight may be recommended to help prevent future gout attacks.
